The Pipeline Pilot components are immediately available for download, free of charge (see below). Please note that all components require a valid license for the corresponding Molecular Networks' software.

• Components for ADRIANA.Code ^NEW!
  for the calculation of a series of molecular descriptors that encode physicochemical, topological, geometrical and surface properties of molecules
  An ADRIANA.Code server setup program for Pipeline Pilot on MS Windows platforms can be requested at info|at|molecular-networks.com.
  (further information about ADRIANA.Code)

• Components for CORINA
  for the generation of high-quality three-dimensional molecular models
  (further information about CORINA)

• Components for SYLVIA ^NEW!
  for the fast estimation of synthetic accessibility of organic compounds
  (further information about SYLVIA)

• Components for isoCYP ^NEW!
  for the prediction of the predominant isoform of humane cytochrome P450 substrates
  (further information about isoCYP)

• Components for MN.2DCOOR
  for the generation of high-quality two-dimensional atomic coordinates
  (further information about MN.2DCOOR)

• Components for MN.CHECK
  for structure integrity checking and normalization of chemical states
  (further information about MN.CHECK)

• Components for MN.CONVERT
  for the interconversion of 40 different file formats for chemical structure and reaction information
  (further information about MN.CONVERT)

• Components for MN.TAUTOMER ^NEW!
  for the enumeration of tautomeric states of organic compounds
  (further information about MN.TAUTOMER)

The following figure shows an example protocol that combines components of MN.CONVERT and CORINA ("run on client method") in a data pipeline (click on the figure to enlarge it).

This example protocol can be downloaded here.

The components were developed and tested using Pipeline Pilot Version 7 on the MS Windows platform (2000/XP). For further information about Pipeline Pilot from Accelrys please visit the Accelrys web site.

Evaluation copies of Molecular Networks' software packages are availabe free of charge in our Download Area.